000			04702cam a2200577Ki 4500
001			9780429341373
003			FlBoTFG
005			20220724194337.0
006			m o d
007			cr cnu|||unuuu
008			191120s2019 xx o 000 0 eng d
040			_aOCoLC-P _beng _erda _epn _cOCoLC-P
020			_a9780429341373 _q(electronic bk.)
020			_a0429341377 _q(electronic bk.)
020			_a9781000680881 _q(electronic bk. : PDF)
020			_a1000680886 _q(electronic bk. : PDF)
020			_a9781000681420 _q(electronic bk. : EPUB)
020			_a1000681424 _q(electronic bk. : EPUB)
020			_z9789814800648
020			_z9814800643
020			_a9781000681154 _q(Mobipocket ebook)
020			_a1000681157
024	8		_a10.1201/9780429341373 _2doi
035			_a(OCoLC)1128095445 _z(OCoLC)1128170416 _z(OCoLC)1128385310
035			_a(OCoLC-P)1128095445
050		4	_aR857.N34
072		7	_aMED _x009000 _2bisacsh
072		7	_aSCI _x008000 _2bisacsh
072		7	_aSCI _x013050 _2bisacsh
072		7	_aPNRP _2bicssc
082	0	4	_a610.28 _223
245	0	0	_aComputational Nanotoxicology : _bChallenges and Perspectives / _cedited by Agnieszka Gajewicz, Tomasz Puzyn.
250			_aFirst edition.
264		1	_a[Place of publication not identified] : _bJenny Stanford Publishing, _c2019.
300			_a1 online resource (xvi, 552 pages).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
505	0		_a1. Modeling of Nanomaterials for Safety Assessment: From Regulatory Requirements to Supporting Scientific Theories Lara Lamon et al. 2. Current Developments and Recommendations in Computational Nanotoxicology in View of Regulatory Application Andrea-Nicole Richarz et al. 3. Physicochemical Properties of Nanomaterials from in silico simulations: An Introduction to Density Functional Theory and Beyond Laura Escorihuela et al. 4. Bionano Interactions: A Key to a Mechanistic Understanding of Nanoparticle Toxicity David Power et al. 5. From Modeling Nanoparticle-Membrane Interactions toward Nanotoxicology Karandeep Singh et al. 6. Descriptors in Nano-QSAR/Nano-QSPR Modeling Ewelina Wyrzykowska et al. 7. Nano-QSAR for Environmental Hazard Assessment: Turning Challenges into Opportunities Willie Peijnenburg, Guangchao Chen and Martina Vijver 8. Read-Across to Fill Toxicological Data Gaps: Good Practice to Ensure Success with Nanoparticles Mark T.D. Cronin et al. 9. Computational Methods of Interspecies Nanotoxicity Extrapolation: A Step toward the Future Supratik Kar, Shinjita Ghosh, and Jerzy Leszczynski 10. On Error Measures for Validation and Uncertainty Estimation of Predictive QSAR Models Supratik Kar, Kunal Roy and Jerzy Leszczynski 11. Green Toxicology Meets Nanotoxicology: The Process of Sustainable Nanomaterial Development and Use Alexandra Maertens and Thomas Hartung 12. Issues for and Examples of Computational Design of "Safe-by-Design" Nanomaterials David A Winkler
520			_aThe development of computational methods that support human health and environmental risk assessment of engineered nanomaterials has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of engineered nanoparticles, computational methods originally developed for regular (i.e., classic) chemicals cannot always be applied explicitly in nanotoxicology. Thus, the main idea of this book is to discuss the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. The book focuses on methodology. Among various in silico techniques, special attention is given to (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics); (ii) nanochemoinformatic methods (quantitative structure-activity relationship modeling, grouping, read-across); and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics).
588			_aOCLC-licensed vendor bibliographic record.
650		0	_aNanomedicine.
650		7	_aMEDICAL / Biotechnology _2bisacsh
650		7	_aSCIENCE / Life Sciences / Biology / General _2bisacsh
650		7	_aSCIENCE / Chemistry / Physical & Theoretical _2bisacsh
700	1		_aGajewicz, Agnieszka, _eeditor.
700	1		_aPuzyn, Tomasz, _eeditor.
856	4	0	_3Read Online _uhttps://www.taylorfrancis.com/books/9780429341373
856	4	2	_3OCLC metadata license agreement _uhttp://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
942			_2lcc _cEBK
999			_c16547 _d16547