000 | 00843nam a2200157Ia 4500 | ||
---|---|---|---|
008 | 220515s9999||||xx |||||||||||||| ||und|| | ||
020 | _a92 4 154678 6 | ||
050 | _aQV 602 .W67 2005 | ||
110 | _aWorld Health Organization | ||
245 | 0 | _aChemical-specific adjustment factors for interspecies differences and human variability | |
260 |
_aGeneva _bWorld Health Organization _c2005 |
||
300 | _aiv, 96p. | ||
500 | _aProvides information intended to guide risk assessors on the integration of quantitative data on interspecies differences or human differences in toxicokinetics and toxicodynamics into dose/concentration-response evaluation through the development of chemical-specific adjustment factors (CSAFs). The kind of data that can be used to develop a CSAF is portrayed. | ||
650 | _aMetabolism|Pharmacokinetics | ||
942 |
_2lcc _cBK |
||
999 |
_c1057 _d1057 |