TY  - BOOK
AU  - Berg,Hugo van den
TI  - Hormones as tokens of selection: qualitative dynamics of homeostasis and regulation in organismal biology 
SN  - 9780429026508
AV  - QP571 
U1  - 612.4/05 23
PY  - 2019///]
CY  - Boca Raton, Florida
PB  - CRC Press
KW  - Hormones
KW  - Genetics
KW  - Homeostasis
KW  - Evolution (Biology)
KW  - MEDICAL / Physiology
KW  - bisacsh
KW  - SCIENCE / Life Sciences / Human Anatomy & Physiology
KW  - MATHEMATICS / General
KW  - MATHEMATICS / Applied
KW  - SCIENCE / Life Sciences / Cytology
N1  - The nature of homeostasis -- Gradient-driven regulatory dynamics -- Coupling and pleiotropy -- Differential inclusions -- Application to mammalian nutrient budgets -- The evolutionary perspective -- Critique and outlook
N2  - Hormones as Tokens of Selection addresses deep questions in biology: How are biological systems controlled? How can one formulate general theories of homeostasis and control and instantiate such theories in mathematical models? How can one use evolutionary arguments to guide our answers to these questions, recognising that the control mechanisms themselves are a product of evolution? Biological systems are exceptionally varied and extremely difficult to understand, because they are complex and experimentation remains limited relative to the challenges at hand. Moreover, biological phenomena occur at a wide range of temporal and spatial scales. Such a deeply convoluted subject calls for a unifying and coherent theoretical foundation -- one which recognises and departs from the primary importance of mathematical modelling and key physicochemical principles to theory formation in the life sciences. This Focus monograph proposes and outlines such a foundation, departing from the deceptively simple proposition that hormones are tokens of evolutionary pressures. Features Provides a coherent and unified approach to a multifaceted problem Pays close attention to both the biological and mathematical modelling aspects of the subject matter, exploring the philosophical background where appropriate Written in a concise and innovative style
UR  - https://www.taylorfrancis.com/books/9780429026508
UR  - http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
ER  -