Slowron, G. (ed)|Ogden, R. (ed) <br/><br/>
Reverse transcriptase inhibitors in HIV/AIDS therapy 

 - New Jersey  Humana Press  2006 
 - xiii, 527p. 
<br/><br/> Gives surveys on aspects of the reverse transcriptase inhibitors (RTIs), a class of drugs used to treat HIV/AIDS. Includes drug discovery, pharmacology, and development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. Combines the understanding of the role of reverse transcriptase in the viral life cycle. Describes the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history. Explains the question of toxicity and resistance to this class of drugs. Addresses three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world. 
<br/><br/><label>ISBN: </label>1-58829-649-0 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acquired Immunodeficiency Syndrome|Drug Therapy|Therapeutics|Anti-Retroviral Agents|HIV|Drug Resistance|Antagonists and Inhibitors
<br/><br/><label>LC Class. No.: </label>WC 503.2 .S56 2006