Antimicrobial resistance - the modern epidermic: current status and research issues

States that Emergence of antibiotic resistant pathogens all over the world is becoming a global problem. The infectious diseases which were thought to have been conquered with the discovery of antibiotics, are back. This is no longer a problem of the developing countries alone because with the rapid travel, international trade. etc., infections have disseminated across the borders. The burden of antibiotic resistance continues to increase and is acknowledged to be a major threat to the treatment of infectious diseases, particularly among patients in hospitals. In the present era of practice of evidence based medicine, there are enough data available to suggest that the risk of adverse outcomes has been found to be higher in patients with infections caused by antibiotic-resistant organisms compared with that by susceptible strains of the same pathogen, even after adjustment for underlying co-morbidities.