Reverse transcriptase inhibitors in HIV/AIDS therapy
Material type:
TextPublication details: New Jersey Humana Press 2006Description: xiii, 527pISBN: - 1-58829-649-0
- WC 503.2 .S56 2006
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AMREF INTERNATIONAL UNIVERSITY (AMIU) LIBRARY | WC 503.2 .S56 2006 (Browse shelf(Opens below)) | Available | 001100 |
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| WC 503.2. O66 1997 Acting on Aids, sex, drugs and politics | WC 503.2 .R33 2001 Adherence and communcation: reports from a study of HIV general practice | WC 503.2 .R45 1997 AIDS under pressure: hyperbaric medicine in the management of HIV infection | WC 503.2 .S56 2006 Reverse transcriptase inhibitors in HIV/AIDS therapy | WC 503.2 .S78 2008 Guidance for Nurse Prescription and Management of Anti-retroviral Therapy | WC 503.2 .U54 2005 Intensifying HIV prevention: UNAIDS policy position paper | WC 503.2 U63 2011 DOHA+10 Trips flexibilities and access to anti-retro viral therapy: Lesson from the past, opportunities for the future |
Gives surveys on aspects of the reverse transcriptase inhibitors (RTIs), a class of drugs used to treat HIV/AIDS. Includes drug discovery, pharmacology, and development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. Combines the understanding of the role of reverse transcriptase in the viral life cycle. Describes the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history. Explains the question of toxicity and resistance to this class of drugs. Addresses three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.
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